REGULATION OF DEPIGMENTATION.
Made in France

VITILSI Gel
15g | 40g

An exclusive natural formulation to favor
repigmentation.

Active ingredients:
A combination of:
• Coleus forskohlii root extract
• Cassia alata pod extract
• A pH of 6.8, ideal for stimulating melanogenesis.




Indications:

VITILSI® Gel is characterized by its mechanism of action that allows it to act at various levels of skin pigmentation.
It stimulates the production and development of epidermal cells (melanocytes and keratinocytes) and then stimulates the production of pigment by melanocytes. It favors the repigmentation of the depigmented or less pigmented areas.
The composition of VITILSI® Gel is based exclusively on plant components.




Properties:

– Increase the expression of SCF.
– Increase the expression of bFGF.
– Increase the number of keratinocytes and/or their stimulation.
– Stimulate the Wnt/β catenin pathway.
– Reduce the levels of TGF-β.
– Reduce the levels of TNF-α.
– Reduce in vivo the levels of IFN-γ.
– Decrease the levels of proinflammatorycytokines.
– Inhibit Nitric Oxide Synthase.
– Increase the expression of MC1R.
– Stimulate the cAMP pathway.
– Have a pH as close as possible to 6.8.
– Restore the physiological levels of MITF.




Directions for use:
SODERMIX® should be applied twice a day on the affected areas. After It is recommended to apply VITILSI® Gel once a day on the required area by performing a light massage to let the product penetrate in an appropriate way. To achieve optimal results, a moderate sun exposure is recommended. It is possible to apply a cream or make-up after complete absorption of the product.




Targets:
Aesthetic Medicine | Dermatology

VITILSI GEL
15g | 40g

An exclusive natural formulation to favor repigmentation.

Active ingredients:
A combination of:
• Coleus forskohlii root extract
• Cassia alata pod extract
• A pH of 6.8, ideal for stimulating melanogenesis.

Indications:

VITILSI® Gel is characterized by its mechanism of action that allows it to act at various levels of skin pigmentation.
It stimulates the production and development of epidermal cells (melanocytes and keratinocytes) and then stimulates the production of pigment by melanocytes. It favors the repigmentation of the depigmented or less pigmented areas.
The composition of VITILSI® Gel is based exclusively on plant components.

Properties:

– Increase the expression of SCF.
– Increase the expression of bFGF.
– Increase the number of keratinocytes and/or their stimulation.
– Stimulate the Wnt/β catenin pathway.
– Reduce the levels of TGF-β.
– Reduce the levels of TNF-α.
– Reduce in vivo the levels of IFN-γ.
– Decrease the levels of proinflammatorycytokines.
– Inhibit Nitric Oxide Synthase.
– Increase the expression of MC1R.
– Stimulate the cAMP pathway.
– Have a pH as close as possible to 6.8.
– Restore the physiological levels of MITF.

Directions for use:
It is recommended to apply VITILSI® Gel once a day on the required area by performing a light massage to let the product penetrate in an appropriate way. To achieve optimal results, a moderate sun exposure is recommended. It is possible to apply a cream or make-up after complete absorption of the product.

Targets:
Aesthetic Medicine | Dermatology

Clinical evidences with VITILSI® Gel:
Clinical results of patients after use VITILSI® Gel for approximately 14 days to 60 days.

Treatment of vitiligo on hand.
Treatment of vitiligo on face. After 1 month of daily VITILSI® application.
Treatment of segmental vitiligo in an adolescent. After 2 month of daily VITILSI® application.
Treatment of segmental vitiligo in an 8-year-old child, (recent occurrence, less than 6 months). After 3 month of daily VITILSI® application.
Treatment of vitiligo on hand. After 14 days of daily VITILSI® application.
Treatment of vitiligo on leg. After 14 days of daily VITILSI® application.

Wordwide advs
VITILSI® Gel for Vietnam. 2022.

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For more info: www.vitilsi.com